ECHA updates REACH SVHC Candidate List: n-hexane and BPAF added (list total reaches 253)

ECHA updated the REACH Candidate List of Substances of Very High Concern (SVHCs) on 4 February 2026 by adding two new entries: (1) n-hexane (EC 203-777-6; CAS 110-54-3) identified under Article 57(f) for specific target organ toxicity after repeated exposure, and (2) 4,4′-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]diphenol and its salts (group entry, commonly referred to as BPAF and its salts), identified under Article 57(c) (toxic for reproduction). The update increases the Candidate List total to 253 entries. Compliance teams should assess impacts on Article 33 communication duties for articles containing these SVHCs and update SVHC screening and supplier declarations accordingly.