NIOSH updates CBRN Respiratory Protection Handbook (expanded CBRN APR Protection List; fit-testing language correction)

NIOSH published a revised version of the Chemical, Biological, Radiological, and Nuclear (CBRN) Respiratory Protection Handbook (NIOSH Publication 2025-111, revised September 2025). The update expands the CBRN air-purifying respirator (APR) protection list (hazards evaluated/covered) and corrects/clarifies fit-testing language (noting OSHA’s acceptance of qualitative fit testing in certain contexts and correcting prior inclusion/misstatement regarding NFPA fit-testing identification for positive-pressure respirators such as SCBA). This is a compliance-relevant NIOSH guidance update for organizations selecting and managing NIOSH-approved CBRN respirator configurations within respiratory protection programs.