OEHHA will host an in-person and online workshop on July 30, 2026, to discuss potential amendments to the Proposition 65 regulations as part of the Omnibus 2026 pre-rulemaking process. OEHHA will publish potential regulatory amendments on its website prior to the workshop. Stakeholders should monitor for proposed changes that may affect warning requirements, listing procedures, or other compliance obligations.
At the request of the Personal Care Products Council, OEHHA has extended the public comment period for proposed No Significant Risk Levels (NSRLs) for 1-bromopropane and diethanolamine under Title 27, California Code of Regulations, section 25705(b)(1). NSRLs establish safe harbor levels below which businesses are not required to provide Proposition 65 warnings for exposures to listed carcinogens.
OEHHA released a draft document for public review that summarizes the carcinogenicity data and derives a cancer inhalation unit risk factor (IUR) for acrolein under Proposition 65. The IUR is a quantitative value used to calculate cancer risk from inhalation exposure, which helps businesses determine whether Proposition 65 warnings are required for products or activities involving acrolein exposures.
OEHHA added the developmental toxicity endpoint to the existing Proposition 65 listing for bisphenol S (BPS) effective December 8, 2025. This expands the reproductive toxicity listing which already included female reproductive toxicity (listed December 29, 2023) and male reproductive toxicity (listed January 3, 2025). Warning requirements for the developmental toxicity endpoint are effective December 8, 2026.
OEHHA added N-methyl-N-formylhydrazine to the Proposition 65 list as a carcinogen effective December 8, 2025. The listing was done via the 'State's Qualified Experts' mechanism based on the Carcinogen Identification Committee's determination that this chemical was clearly shown to cause cancer. Businesses have a one-year grace period until December 8, 2026 to provide warnings for significant exposures.
OEHHA issued an information letter regarding Proposition 65 warning requirements for items such as receipts and shipping labels that may contain bisphenol S (BPS). The letter provides guidance on warning obligations following the listing of BPS for reproductive toxicity endpoints.
OEHHA added the developmental toxicity endpoint to the existing reproductive toxicity listing for Bisphenol S (BPS) under Proposition 65. This addition was made via the State's Qualified Experts listing mechanism based on the Developmental and Reproductive Toxicant Identification Committee's determination that BPS was clearly shown to cause developmental toxicity. Products containing BPS sold in California may now require warnings for developmental toxicity exposures in addition to reproductive toxicity.
OEHHA added N-Methyl-N-Formylhydrazine to the Proposition 65 list as known to cause cancer. This chemical is now subject to California's warning requirements under Prop 65. Businesses with products containing this substance that may result in exposures in California should evaluate their warning obligations.
OEHHA proposes to adopt No Significant Risk Levels (NSRLs) for 1-bromopropane and diethanolamine (dermal route) by amending Title 27, California Code of Regulations, section 25705(b). Public comment period deadline is October 6, 2025. These safe harbor levels would help businesses determine when Prop 65 warning requirements apply.
OEHHA proposed amendments to Title 27, California Code of Regulations, Section 25705(b) to adopt No Significant Risk Levels (NSRLs) for 1-bromopropane (54 micrograms per day) and diethanolamine for dermal exposure (6.4 micrograms per day). The diethanolamine NSRL applies only to dermal routes of exposure. The public comment period was extended to November 7, 2025 at the request of industry stakeholders.
OEHHA adopted a No Significant Risk Level (NSRL) for Titanium Dioxide (airborne, unbound particles of respirable size) under Proposition 65. The NSRL establishes a safe harbor level for cancer risk from inhalation exposure, allowing businesses to determine if exposures require Proposition 65 warnings. The regulation was approved by the Office of Administrative Law on June 18, 2025 and took effect on October 1, 2025.
OEHHA adopted a No Significant Risk Level (NSRL) for titanium dioxide (airborne, unbound particles of respirable size). The NSRL provides a safe harbor level allowing businesses to determine if Prop 65 cancer warning requirements apply for exposures below the NSRL threshold. Effective October 1, 2025.
OEHHA has added Bisphenol S (BPS) to the Proposition 65 list for reproductive toxicity (male and female endpoints). Products containing BPS that may cause significant exposures require Proposition 65 warnings when sold in California. BPS is commonly used as a BPA replacement in thermal paper, plastics, and other consumer products.
OEHHA adopted amendments to Title 27, California Code of Regulations sections 25601, 25602, 25603, and 25607.2, adding new sections 25607.50-25607.53 governing short-form warning statements. The amendments were approved by the Office of Administrative Law on November 26, 2024 and became effective January 1, 2025. A three-year implementation period allows businesses to transition until January 1, 2028, after which the old short-form warning format may no longer be used. The amendments also add new tailored safe harbor warnings for passenger and off-highway motor vehicle parts and recreational marine vessel parts.