EPA final rule updates TSCA New Chemicals Regulations (40 CFR Parts 720, 721, 723, 725), including PFAS/PBT ineligibility for certain exemptions and strengthened premanufacture determination requirements

EPA finalized amendments to the TSCA New Chemicals Regulations (40 CFR Parts 720, 721, 723, and 725). As highlighted by EPA, the changes remove eligibility for certain exemptions (e.g., LVE/LoREX) for PFAS and other PBT chemicals and require EPA to make one of the five statutory determinations for PMNs/SNUNs/MCANs before manufacture/processing begins. Compliance teams submitting PMNs/SNUNs or relying on exemptions should reassess exemption strategies, timelines, and documentation in light of the updated rules.