Regulation ChangeLiveLive Regulation
EPA Issues Final SNURs Batch 24-4.5e for Chemical Substances
TSCA Section 5 — Significant New Use Rules (40 CFR Part 721)U.S. Environmental Protection Agency (EPA)US
Announced
Nov 4, 2025
Description
EPA published final significant new use rules (SNURs) for chemical substances that were the subject of premanufacture notices (PMNs), TSCA Orders, and proposed rules (Batch '24-4.5e'). The SNURs require anyone intending to use the chemicals under certain conditions to notify EPA at least 90 days before beginning that use, allowing EPA to evaluate potential risks from the new use. Published in the Federal Register (90 FR 14743).
Sources
Key Findings
EPA Issues Final SNURs Batch 24-4.5e for Chemical Substances
ly on official, secure websites. # Recent Activities for the New Chemicals Program under the Toxic Substances Control Act **November 4, 2025** – EPA published [final significant new use rules (SNURs)](https://www.regulations.gov/document/EPA-HQ-OPPT-2024-0332-0067) (Batch “24-4.5e”) for chemical substances that were the subject of premanufacture notices (PMNs), TSCA Orders, and proposed rules (90 FR 14743). The SNURs