EPA proposed multiple SNUR batches (published Nov. 3, 2025) and proposed amendments to existing SNURs (published Oct. 28, 2025). If finalized, these proposals would impose or modify TSCA Section 5 Significant New Use Notice (SNUN) requirements for specified chemical substances/uses. Compliance teams should monitor the relevant dockets, evaluate whether their substances/uses could be affected, and consider submitting comments as appropriate.
EPA proposed amendments/modifications to existing SNUR requirements (batch 23-1.M). The proposal would adjust significant new use designations for covered substances and opened a public comment period (deadline stated as Nov. 28, 2025). Companies should review whether amended SNUR triggers could affect current or planned uses and consider submitting comments and preparing for potential final changes.
EPA proposed amendments to the TSCA risk evaluation procedures rule (the ‘Framework Rule’) that governs how EPA conducts existing-chemical risk evaluations. The proposal (per EPA’s release) would adjust key procedural elements such as conditions-of-use determinations and other evaluation process components, and opens a public comment period. Compliance teams should assess how the proposed procedural changes could affect the scope, pace, and content of future TSCA risk evaluations relevant to their chemical portfolios and consider submitting comments.
EPA issued a proposed rule to amend procedures for conducting chemical risk evaluations for existing chemicals under TSCA. This proposal would revise the risk evaluation framework and could affect how companies plan for risk evaluation scope, data submissions, use categorization, and downstream risk management implications. Compliance teams should review the proposal and consider participating in the public comment process for impacts to ongoing and future TSCA risk evaluations.
EPA announced a proposed rule to revise the process/procedures for conducting TSCA risk evaluations for chemicals already in commerce (existing chemicals), intended to increase efficiency and better protect health and the environment. The proposal opens a public comment period (duration described by EPA in the news release). Compliance teams should assess how potential changes could affect scope, pace, and data expectations for TSCA risk evaluations, and consider submitting comments via the associated docket if affected.
EPA announced a proposed rule to revise the procedures for conducting TSCA risk evaluations for existing chemicals (the TSCA risk evaluation framework/procedural rule). The proposal describes changes affecting how EPA makes risk determinations (including around conditions of use and exposure pathways), treatment of occupational exposure controls (e.g., PPE/engineering controls), and related procedural/definition updates. Companies with substances undergoing TSCA risk evaluation should assess potential impacts on evaluation scope and assumptions and consider submitting comments in the associated docket once the proposal is published in the Federal Register.
EPA announced a policy to prioritize review of new chemicals used in data center projects under TSCA. This prioritization supports American manufacturing and technological advancement by accelerating TSCA review timelines for chemicals essential to data center operations.
EPA announced availability of the latest biannual update to the public (non-confidential) portion of the TSCA Inventory, including updates to commercial activity status and regulatory flags (e.g., SNUR and test order indicators). Compliance teams that screen products or raw materials against the TSCA Inventory should refresh internal reference datasets and verify substance status and regulatory flags against the latest posting.
EPA released its latest biannual update to the TSCA Chemical Substance Inventory, which contains all existing chemical substances manufactured, processed, or imported in the U.S. under TSCA that do not qualify for an exemption or exclusion. The non-confidential portion of the Inventory is publicly available on EPA's website. This regular update ensures timeliness and accuracy of chemical substance information for regulatory compliance purposes.
EPA announced availability of the latest update to the public (non-confidential) TSCA Inventory as part of its biannual posting cycle, including updates to inventory totals and associated data elements (e.g., commercial activity, unique identifier data, regulatory flags). EPA also notes the next regular update is planned for winter 2026. Compliance teams should refresh internal inventory reference datasets and re-check substance listing status and applicable flags used to support TSCA Inventory determinations.
EPA announced significant process improvements to accelerate Low Volume Exemption (LVE) reviews under TSCA. The agency completed risk assessments for 106 LVEs in just two months and increased the average number of LVE risk assessments from 15 per month to 53 per month, representing an increase of over 250%. This operational change reduces backlogs and accelerates time-to-market for new chemicals qualifying for LVE status while maintaining safety reviews.
EPA has revised the guidelines for making corrections to the TSCA Chemical Substance Inventory. The updated guidelines provide procedures for manufacturers and importers to correct errors or update information in their Inventory submissions, ensuring accurate chemical substance records.
EPA opened a 30-day public comment period on its 2024 final risk management rule for perchloroethylene (PCE) under TSCA. This is the first step in EPA's efforts to reconsider and, if appropriate, revise the final risk management rule. The review is being done in accordance with applicable law, Executive Orders, and Administration policies, including Executive Order 14219 on ensuring lawful governance.
EPA released new resources to assist companies submitting new chemical notices (PMNs) under TSCA. The resources are designed to improve submission quality and efficiency in the premanufacture notification process, helping companies comply with TSCA Section 5 requirements.
EPA withdrew the previously proposed Significant New Use Rules (SNURs) for 18 chemical substances (SNUR batch 23-2.5e). EPA stated the withdrawal was due to the withdrawal of the underlying TSCA section 5(e) order that formed the basis for the proposed SNURs. For compliance teams tracking these proposed SNUR notification obligations, the withdrawal means the proposed significant new use notification requirements will not proceed as proposed, unless EPA initiates a new action in the future.
EPA withdrew the proposed Significant New Use Rules (SNURs) under TSCA for 18 chemical substances that were proposed on June 20, 2023. EPA withdrew the proposed rules because the Agency withdrew the TSCA Order that was the basis of the rules on December 18, 2024. The original proposed rules were published at 88 FR 39804 on June 20, 2023.
EPA issued additional test orders to support risk evaluations of eight chemicals under TSCA. The test orders require manufacturers to conduct testing and submit data that will inform EPA's risk evaluation process for these chemicals under TSCA Section 4.
EPA issued an interim final rule that delays the TSCA §8(a)(7) one-time PFAS reporting submission period. The submission window start moved from July 11, 2025 to April 13, 2026. EPA states most reporters must submit by Oct. 13, 2026, while small manufacturers reporting exclusively as PFAS article importers have until Apr. 13, 2027. Compliance teams should adjust internal data-collection and supplier engagement timelines for the 2011–2022 PFAS manufacture/import lookback accordingly.
EPA’s TSCA §8(a)(7) PFAS reporting program page describes the current reporting window and extended submission deadlines established via an interim final rule. Per the research text, submissions are due by Oct 13, 2026 for most manufacturers (including importers), and by Apr 13, 2027 for small manufacturers that only need to report PFAS in imported articles. Companies in scope should align data collection and internal reporting systems to the updated reporting window and submission deadlines and monitor ongoing rulemaking that could further alter scope.
The U.S. Government Accountability Office (GAO) issued a report (GAO-25-106839) finding that EPA's TSCA New Chemicals Program does not follow key management practices. Chemical manufacturers raised concerns about unclear requirements and review delays. GAO found EPA lacks a systematic process to manage and assess program performance, which may impede effective implementation. Companies submitting new chemical notifications should be aware of ongoing program challenges and potential process changes.